Clinical Trial

Tolerability and Feasibility Pilot Clinical Study of a Large-Diameter Nerve Cap for Protecting and Preserving Terminated Nerve Ends

Study acronym: REPOSE-XL℠
Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
This pilot study evaluates the tolerability and feasibility of the Axoguard Large-Diameter Nerve Cap (sizes 5-7 mm) for protecting and preserving terminated nerve endings after limb trauma or amputation when immediate attention to the nerve injuries is not possible.
Protocol Amendment History 8 amendments
This ClinicalTrials.gov record has been amended 8 times since 2021-04-26; most recent amendment 2026-06-01.
Status change: Recruiting → Active, Not Recruiting 2025-04-29
Status change: Not Yet Recruiting → Recruiting 2022-03-02
Trial Details
NCT Number NCT04865679
Lead Sponsor Axogen Corporation
Conditions Symptomatic Neuroma, Amputation, Chronic Nerve Pain
Enrollment 15 participants
Start Date 2022-03-02
Primary Completion 2026-12 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2026-06-03