Clinical Trial

Intraoperative Radiotherapy in Patients With Brain Metastases

Recruiting
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Record status
This record was last updated June 6, 2025 (before its estimated December 2025 completion). Its status may not reflect the trial's current state.
Summary
Intraoperative radiotherapy (IORT) is a new alternative for local radiotherapy with the advantages of dose escalation, reduced overall treatment time, and enhanced patient convenience, however the degree of efficacy is unknown, as well as and which is the most efficient dose. The objective of this study is to evaluate the efficacy and safety of IORT in patients with surgical excision of brain metastases at a dose of 20 Gy is at least as effective and safe as other forms of radiation therapy in patients with resection of brain metastases.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2021-04-15; most recent amendment 2025-06-05.
Trial Details
NCT Number NCT04847284
Lead Sponsor Parc de Salut Mar
Conditions Brain Metastases
Enrollment 25 participants
Start Date 2021-05-05
Primary Completion 2025-12 (estimated)
Study Completion 2025-12 (estimated)
Updated on ClinicalTrials.gov 2025-06-06