LIA vs. LIA + ACB-iPACK Block for Total Knee Arthroplasty

LIA is the mainstay of postoperative analgesia in patients having knee arthroplasty. The combination of ACB-iPACK blocks has also been proposed as an effective analgesic modality for total knee arthroplasty. However, whether combining these two modalities yields any important incremental analgesic benefit remains unclear. The investigators hypothesized that the addition of ACB and iPACK blocks to LIA will yield clinically important analgesic benefits compared to LIA alone in patients having total knee arthroplasty.

NCT Number	NCT04808947
Lead Sponsor	Women's College Hospital
Conditions	Nerve Block, Neuromuscular Blockade
Enrollment	60 participants
Start Date	2027-01
Primary Completion	2027-12 (estimated)
Study Completion	2028-12 (estimated)
Updated on ClinicalTrials.gov	2025-07-16