Clinical Trial

Dose-Escalated Spine SbRT for Localized Metastasis to the Spinal Column

Study acronym: DESSRT

Recruiting

Summary

This study is being done to determine the feasibility and tolerability of a novel regimen of spine stereotactic radiosurgery (SSRS). SSRS delivers high doses of radiation to tumors of the spine using precision techniques. In standard medical care, conventional SSRS is delivered in only 1 or 2 treatments. When this treatment is delivered in only 1-2 treatments, a high dose is used which can increase the side effects of treatment. This study aims to test an alternative technique of delivering SSRS over 5 treatments. By delivering the radiation therapy over multiple treatments, the dose of radiation is less per treatment.

Protocol Amendment History 7 amendments

This ClinicalTrials.gov record has been amended 7 times since 2021-03-15; most recent amendment 2025-11-13.

Trial Details

NCT Number	NCT04802603
Lead Sponsor	Baptist Health South Florida
Conditions	Spine Metastases, Metastasis Spine
Enrollment	60 participants
Start Date	2021-03-14
Primary Completion	2029-09-28 (estimated)
Study Completion	2029-12-31 (estimated)
Updated on ClinicalTrials.gov	2025-11-14