Clinical Trial

Contribution of ICG Angiography in the Detection of Parathyroids and the Prevention of Hypoparathyroidism Post Total Thyroidectomy

Study acronym: HYPOCAAVI
Recruiting Phase 3
View on ClinicalTrials.gov →
Record status
This record was last updated March 19, 2026 (before its estimated June 22, 2026 completion). Its status may not reflect the trial's current state.
Summary
* Hypoparathyroidism is the most common complication after a total thyroidectomy surgery. It becomes permanent after 6 months. * Untreated permanent hypoparathyroidism is a source of numerous complications in general and therefore requires lifelong replacement therapy resulting in a significant deterioration in quality of life. * The intraoperative use of indocyanine green (ICG) angiography has recently been described as a reliable means of detecting parathyroidism and predicting the risk of postoperative hypoparathyroidism. * This use could prove to be a way to preserve parathyroid in vivo and thus reduce post-operative hypoparathyroidism rates.
Protocol Amendment History 7 amendments
This ClinicalTrials.gov record has been amended 7 times since 2021-03-04; most recent amendment 2026-03-18.
Status change: Not Yet Recruiting → Recruiting 2021-04-21
Trial Details
NCT Number NCT04785443
Lead Sponsor University Hospital, Brest
Conditions Thyroid Diseases
Enrollment 242 participants
Start Date 2021-06-22
Primary Completion 2026-06-22 (estimated)
Study Completion 2027-06-22 (estimated)
Updated on ClinicalTrials.gov 2026-03-19