Clinical Trial

Testing FIRST in Youth Outpatient Psychotherapy

Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
The study will compare the impact FIRST (a transdiagnostic treatment built upon five empirically supported principles of change) versus usual care outpatient psychotherapy on youths' mental health outcomes and a candidate mechanism of change: regulation of negative emotions.
Protocol Amendment History 8 amendments
This ClinicalTrials.gov record has been amended 8 times since 2021-01-23; most recent amendment 2026-04-14.
Status change: Recruiting → Active, Not Recruiting 2026-04-14
Status change: Not Yet Recruiting → Recruiting 2021-10-08
Trial Details
NCT Number NCT04725721
Lead Sponsor Harvard University
Collaborators: University of Texas at Austin
Conditions Anxiety, Depression, Trauma, Behavior Problem
Enrollment 212 participants
Start Date 2021-09-27
Primary Completion 2027-02 (estimated)
Study Completion 2027-02 (estimated)
Updated on ClinicalTrials.gov 2026-04-17