CHronic Nonbacterial Osteomyelitis International Registry

The objective of the study is to establish a prospective disease registry for chronic recurrent multifocal osteomyelitis (CRMO)/chronic nonbacterial osteomyelitis (CNO) in order to investigate the natural history of the disease and the responses of patients to different clinical managements over 10 years.

NCT Number	NCT04725422
Lead Sponsor	Seattle Children's Hospital Collaborators: Boston Children's Hospital, Boston, MA, USA, Hospital for Special Surgery, New York, Joseph M Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack, NJ, USA, Riley Children's Hospital, Indianapolis, IN, USA, University of North Carolina, Chapel Hill, NC, USA, Royal Children's Hospital, Hacettepe University, Bambino Gesù Children's Hospital, Rome, Italy, University of British Columbia, Vancouver, BC, Canada, Meyer Children's Hospital, Florence, Italy, Mansoura University, University of Utah, Salt Lake City, UT, USA, University of Iowa Carver College of Medicine, Iowa City, IA, USA, Ann & Robert H Lurie Children's Hospital of Chicago, Palacky University Olomouc Institute of Molecular and Translational Medicine, Olomouc, Czechia, Alder Hey Children's NHS Foundation Trust, University of Calgary
Conditions	Chronic Nonbacterial Osteomyelitis, Chronic Recurrent Multifocal Osteomyelitis
Enrollment	2,000 participants
Start Date	2018-08-01
Primary Completion	2028-08 (estimated)
Study Completion	2050-08 (estimated)
Updated on ClinicalTrials.gov	2024-07-30