Clinical Trial

Bone Density and Vascular Calcifications Evolution After Renal Transplant

Recruiting
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Record status
This record was last updated December 18, 2024 (before its estimated December 12, 2025 completion). Its status may not reflect the trial's current state.
Summary
The investigators project is based on: * Assessment of bone architecture by high resolution peripheral scanner (HRpQCT) and bone densitometry (DEXA); * The non-invasive detection of vascular calcifications (by abdominal CT scanner) and bone abnormalities associated with kidney transplantation, as well as the analysis of evolution over time; * Longitudinal evaluation of nephrological clinical parameters (glomerular filtration rate, number and type of rejections, immunosuppressive medications) as well as biological and urinary parameters of mineral metabolism (parathormone, sclerostin, bone alkaline phosphatase) depending on the type and severity of bone abnormalities; * The evaluation of these nephrological clinical parameters and of the biological parameters of mineral metabolism depending on the extent and evolution of vascular calcifications but also on bone morphology; * The study of possible relationships between bone mass and muscle mass (and functioning)
Protocol Amendment History 4 amendments
This ClinicalTrials.gov record has been amended 4 times since 2021-01-13; most recent amendment 2024-12-13.
Trial Details
NCT Number NCT04713774
Lead Sponsor University of Liege
Conditions Kidney Transplant; Complications, Bone Loss
Enrollment 50 participants
Start Date 2020-09-01
Primary Completion 2025-12-12 (estimated)
Study Completion 2026-12-13 (estimated)
Updated on ClinicalTrials.gov 2024-12-18