Clinical Efficacy and Long Term Effects of Transcranial Direct Current Stimulation (tDCS) in Children With Attention Deficit/Hyperactivity Disorder (ADHD)

Attention-Deficit/Hyperactivity Disorder (ADHD) is the most commonly diagnosed neurodevelopmental disorder in childhood. Patients with ADHD present inattention, impulsivity and hyperactivity causing severe impairments on academic achievement, social and professional life and daily functioning. Medications are effective in a majority of children with ADHD, but about 30% do not respond or tolerate stimulants, and some parents refuse pharmacological treatments.Transcranial Direct Current Stimulation is a safe and non-invasive technique of brain stimulation used in several neurological and psychiatric disorders, and recently in ADHD. In patients with ADHD, tDCS stimulations targeted frontal regions improve executive and attentional functioning and daily life symptoms. The objective of this project is to evaluate the efficacy of tDCS (vs sham) during cognitive-remediation exercises on ADHD symptoms (inattention, impulsivity and hyperactivity as defined by DSM-5) in children with ADHD between 7 and 14 years of age.

NCT Number	NCT04704687
Lead Sponsor	Centre Hospitalier Universitaire, Amiens Collaborators: Hospices Civils de Lyon, Nantes University Hospital, Centre Hospitalier Charles Perrens, Bordeaux, University Hospital, Lille
Conditions	Attention Deficit Hyperactivity Disorder, Transcranial Direct Current Stimulation
Enrollment	150 participants
Start Date	2021-01-08
Primary Completion	2025-08 (estimated)
Study Completion	2026-01 (estimated)
Updated on ClinicalTrials.gov	2025-05-29