Assess Use of 18F-Fluciclovine for Patients With Large Brain Metastases Treated With Staged Stereotactic Radiosurgery

The spread of cancer to the brain is referred to as brain metastases. Brain metastases are a common complication of cancer. This study is being done to determine whether the use of a new imaging agent, 18F-fluciclovine, is able to detect which patients are responding to radiation therapy. In addition, this study will look at the changes of the treated brain metastases using this imaging agent over time.

NCT Number	NCT04689048
Lead Sponsor	Baptist Health South Florida Collaborators: Blue Earth Diagnostics
Conditions	Brain Metastases, Adult, Brain Metastases, Brain Cancer
Enrollment	20 participants
Start Date	2022-04-04
Primary Completion	2027-03 (estimated)
Study Completion	2027-12 (estimated)
Updated on ClinicalTrials.gov	2026-04-22