Clinical Trial

Stopping Opioid Overuse in Obstetrics to Halt Exposure Trial

Study acronym: SOOOTHE
Active, Not Recruiting Phase 4
View on ClinicalTrials.gov →
Record status
This record was last updated March 25, 2025 (before its estimated June 1, 2025 completion). Its status may not reflect the trial's current state.
Summary
As the opioid epidemic continues on, more research is needed on multi-modal approaches to decrease opioid exposure after common procedures. The aim of this study is to investigate the role of a transverses abdominis block using liposome bupivacaine suspension in reducing use of opioid medications through post-operative day 7. The study is a proposed double-blind, randomized controlled trial.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2020-12-19; most recent amendment 2025-03-20.
Status change: Enrolling by Invitation → Active, Not Recruiting 2025-03-20
Status change: Not Yet Recruiting → Enrolling by Invitation 2021-02-28
Trial Details
NCT Number NCT04680221
Lead Sponsor University of Missouri, Kansas City
Collaborators: Truman Medical Center
Conditions Pain, Postoperative, Opioid Use
Enrollment 97 participants
Start Date 2021-03-01
Primary Completion 2025-06-01 (estimated)
Study Completion 2025-06-01 (estimated)
Updated on ClinicalTrials.gov 2025-03-25