Clinical Trial

Sequential Analysis Before and After Treatment Initiation to Unravel the Role of Naturally Occurring Extracellular Vesicles in HIV Infection

Study acronym: Saturne-HIV
Recruiting
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Summary
This study aims to evaluate the role of extracellular vesicles in HIV-infection, by determining the expression profile and content of EVs before and after treatment initiation in HIV-infected patients, through extensive blood and tissue sampling (leukapheresis, stool sampling and colon biopsies). A one-time sampling (blood, stool, colon biopsies) will also be performed in HIV-seronegative healthy volunteers to confirm that results found in HIV-infected patients are related to the disease.
Protocol Amendment History 6 amendments
This ClinicalTrials.gov record has been amended 6 times since 2020-11-26; most recent amendment 2024-02-06.
Status change: Not Yet Recruiting → Recruiting 2021-05-31
Trial Details
NCT Number NCT04653610
Lead Sponsor University Hospital, Ghent
Conditions Hiv
Enrollment 105 participants
Start Date 2021-01-27
Primary Completion 2027-01-01 (estimated)
Study Completion 2027-01-01 (estimated)
Updated on ClinicalTrials.gov 2024-02-08