Clinical Trial

Comprehensive Esophageal Diagnostics Study

Recruiting Phase 4
View on ClinicalTrials.gov →
Summary
The prospective clinical trial will study muscle fibrosis in relation to lower esophageal sphincter (LES) measurements on Functional Lumen Imaging Probe (FLIP) Topography (the novel technology that utilizes impedance planimetry) after pharmacologic challenge. A better understanding of achalasia will allow intervention at an earlier stage.
Protocol Amendment History 9 amendments
This ClinicalTrials.gov record has been amended 9 times since 2020-11-18; most recent amendment 2025-11-05.
Status change: Suspended → Recruiting 2022-03-09
Status change: Recruiting → Suspended 2022-01-19
Status change: Not Yet Recruiting → Recruiting 2021-03-05
Trial Details
NCT Number NCT04641702
Lead Sponsor Emory University
Collaborators: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions Achalasia
Enrollment 80 participants
Start Date 2021-03-17
Primary Completion 2026-09-30 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2025-11-10