Diagnosis and OutcoMes evaluAtIoN of Multicenter Patients With HFpEF Using Multimodality Imaging

The incidence of Heart failure with preserved ejection fraction (HFpEF) in Heart failure patients increases rapidly. However, the current clinical awareness is insufficient, and the cardiac structural and functional injury are not well understood. It is difficult to recognize the subclinical changes of the cardiac in the early stage with conventional imaging techniques, and it is common to ignore the existence of the clinical alterations. This study aimed to investigate the cardiac features, early diagnosis and risk factors of HFpEF patients, based on the multi-modality (Magnetic resonance imaging- nuclear medicine imaging- echocardiography) imaging and multicenter study, combined with large data and artificial intelligence. This study will provide deep insights into the HFpEF in multicenter population.

NCT Number	NCT04602338
Lead Sponsor	Chinese Academy of Medical Sciences, Fuwai Hospital Collaborators: Peking Union Medical College Hospital, Beijing Anzhen Hospital, China-Japan Friendship Hospital, Guangdong Provincial People's Hospital
Conditions	Heart Failure, Diastolic, Multicenter Study
Enrollment	1,000 participants
Start Date	2020-11-01
Primary Completion	2027-06 (estimated)
Study Completion	2028-06 (estimated)
Updated on ClinicalTrials.gov	2022-04-18