Clinical Trial

Predicting Acute-on-Chronic Liver Failure After Surgical Intervention in Chronic Liver Disease

Study acronym: PERSEVERE
Recruiting
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Record status
This record was last updated May 18, 2022 (before its estimated December 31, 2025 completion). Its status may not reflect the trial's current state.
Summary
Prospective, observational study to define precipitants and predictors of development of Acute-on-Chronic Liver Failure (ACLF) after surgical interventions, allowing to develop a risk stratification for elective procedures in cirrhotic patients. As well as identifying molecular mechanisms of post-interventional ACLF and thus preparing the ground for development of new therapeutic approaches.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2020-09-30; most recent amendment 2022-05-17.
Trial Details
NCT Number NCT04578301
Lead Sponsor University Hospital, Bonn
Conditions Liver Cirrhosis, Portal Hypertension, Surgery, Acute-On-Chronic Liver Failure, Non-Cirrhotic Portal Hypertension
Enrollment 200 participants
Start Date 2020-09-22
Primary Completion 2025-12-31 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2022-05-18