Clinical Trial

Understanding the Neural Mechanisms Behind tDCS

Recruiting
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Record status
This record was last updated August 30, 2024 (before its estimated December 31, 2024 completion). Its status may not reflect the trial's current state.
Summary
The aim of the study is to investigate the neural mechanisms underpinning transcranial direct current stimulation (tDCS), a non-invasive neuromodulation technique in which a direct current is passed through scalp electrodes. A series of experiments will be conducted to understand and characterize the transcranial and transcutaneous mechanisms of tDCS. To investigate this research question, every participant will undergo three stimulation conditions (active, sham and control). In the control condition, an anaesthetic cream will be applied to anaesthetize the nerves in the scalp. In addition, the effectiveness of tDCS and peripheral nerve stimulation will be compared. Ultimately, the obtained knowledge can lead to the development of improved non-invasive neuromodulation therapies, which can lead to more effective treatments of a variety of neurological and psychiatric disorders.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2020-10-02; most recent amendment 2024-08-29.
Trial Details
NCT Number NCT04577677
Lead Sponsor KU Leuven
Conditions tDCS Mechanisms
Enrollment 130 participants
Start Date 2020-09-01
Primary Completion 2024-12-31 (estimated)
Study Completion 2024-12-31 (estimated)
Updated on ClinicalTrials.gov 2024-08-30