Supportive-Expressive and Emotion-Focused Treatment for Depression

This study will explore the mechanisms of change that are activated when individuals receive a treatment that targets their weakness and the mechanisms activated when the treatment capitalize on their strength. Patients will be assigned to one of two types of psychotherapies in treating people with a major depression disorder, expressive-supportive vs. emotion-focused treatment. Their ability to benefit from treatment based on their pre-treatment levels of insight and emotional processing will be examined. This is a four-month protocol, with a 2 year follow up period.

NCT Number	NCT04576182
Lead Sponsor	University of Haifa Collaborators: Israel Science Foundation
Conditions	Major Depressive Disorder
Enrollment	124 participants
Start Date	2020-11-29
Primary Completion	2026-11-30 (estimated)
Study Completion	2027-05-31 (estimated)
Updated on ClinicalTrials.gov	2026-05-07