Clinical Trial

The HistoSonics System for Treatment of Primary and Metastatic Liver Tumors Using Histotripsy (#HOPE4LIVER EU/UK)

Study acronym: #HOPE4LIVER
Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
This trial is a single arm, non-randomized prospective trial. The objective of this trial is to evaluate the efficacy and safety of the HistoSonics System for the treatment of primary or metastatic tumors located in the liver.
Protocol Amendment History 21 amendments
This ClinicalTrials.gov record has been amended 21 times since 2020-09-28; most recent amendment 2025-12-18.
Status change: Recruiting → Active, Not Recruiting 2023-04-04
Status change: Not Yet Recruiting → Recruiting 2021-07-01
Trial Details
NCT Number NCT04573881
Lead Sponsor HistoSonics, Inc.
Conditions Liver Neoplasms, Hepatocellular Carcinoma, Liver Metastases
Enrollment 24 participants
Start Date 2021-06-04
Primary Completion 2022-09-29 (estimated)
Study Completion 2027-08 (estimated)
Updated on ClinicalTrials.gov 2026-01-12