Clinical Trial

The Clinical Influence of Developing a Sustainable Cardiac Surgery Service to Reduce the Burden of Rheumatic Heart Disease in Sub-Saharan Africa

Study acronym: RHD-CaSS
Recruiting
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Record status
This record was last updated June 12, 2025 (before its estimated December 31, 2025 completion). Its status may not reflect the trial's current state.
Summary
In this bi-directional program of education, training and research activities based on sustainable development goals aim is to develop cardiac surgery service in Ethiopia. The aim is to evaluate the short and long-term outcome of cardiac surgery for rheumatic heart disease in a low-income country compared to individuals not offered cardiac surgery due to limited availability of the service. Second aim is to evaluate the quality of anticoagulant therapy in patients after cardiac surgery for rheumatic heart disease in a low-income country .
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2020-09-15; most recent amendment 2025-06-11.
Status change: Active, Not Recruiting → Recruiting 2022-04-07
Status change: Recruiting → Active, Not Recruiting 2021-11-05
Trial Details
NCT Number NCT04556188
Lead Sponsor Helse Nord-Trøndelag HF
Collaborators: Haukeland University Hospital, Addis Ababa University
Conditions Rheumatic Heart Disease, Anticoagulant Adverse Reaction
Enrollment 200 participants
Start Date 2016-03-01
Primary Completion 2025-12-31 (estimated)
Study Completion 2026-06-30 (estimated)
Updated on ClinicalTrials.gov 2025-06-12