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A Study of Health-Related Quality of Life in People With Multiple Myeloma Receiving Daratumumab or Lenalidomide

StatusActive, Not Recruiting
PhasePhase 2
Started2020-08-28
View on ClinicalTrials.gov ↗
The purpose of this study is to compare maintenance therapy approaches in people with newly diagnosed multiple myeloma (MM) that has responded well to a first round of treatment. The researchers will compare giving the usual maintenance therapy (lenalidomide) with giving daratumumab as maintenance therapy, and they will look at which drug gives participants a better health-related quality of life during treatment. The researchers will measure participants' quality of life using various questionnaires. This study will help researchers find out whether this different approach of giving daratumumab as maintenance therapy is better, the same as, or worse than the usual approach.

Amendment history 2 changes detected by DataLookout

2026-09-16
critical
Primary completion pushed: 2026-08 → 2027-08
2026-09-16
minor
Completion pushed: 2026-08 → 2027-08
Trial Details
NCT Number NCT04497961
Lead Sponsor Memorial Sloan Kettering Cancer Center
Collaborators: Janssen Scientific Affairs, LLC
Conditions Multiple Myeloma
Enrollment 95 participants
Start Date 2020-08-28
Primary Completion 2027-08 (estimated)
Study Completion 2027-08 (estimated)
Updated on ClinicalTrials.gov 2026-09-15