Transcranial Magnetic Stimulation in Progressive Supranuclear Palsy

StatusRecruiting
PhaseNot applicable
Started

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Trial flagged as At Risk
Primary completion moved at least 2 months later Jan 6, 2027 → Apr 2027
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Record History

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  1. Primary completion pushed from Jan 6, 2027 to Apr 2027
    • Study completion pushed from Apr 20, 2027 to Oct 2027
    • Eligibility criteria expanded, about 10 words
    • Site details revised
  2. Site contact updatedv7
  3. Primary completion date: Jan 2027 to Jan 6, 2027
    • Study completion date: Apr 2027 to Apr 20, 2027
    • Collaborators: 5 to 7
    v6
  4. Primary completion date: Jan 2026 to Jan 2027
    • Study completion date: Jun 2026 to Apr 2027
    • Secondary endpoints revised (2)
    v5
  5. Eligibility criteria expanded, about 9 words
    • Collaborators: 4 to 5
    v4
Show 2 earlier versionsHide 2 earlier versions
  1. Site contact updatedv3
  2. Re-verified, no change to tracked fieldsv2
  1. Study First Submitted
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The objective of this proposal is to investigate the effect of non-invasive repetitive cerebellar transcranial magnetic stimulation (rTMS) on motor control in progressive supranuclear (PSP). The central hypothesis is that augmenting cerebellar inhibition via cerebellar rTMS will decrease postural instability in patients with PSP. We will use functional near infrared spectroscopy (fNIRS) to examine changes in motor and premotor cortical activity after cerebellar rTMS.
Trial Details
NCT Number NCT04468932
Lead Sponsor Oregon Health and Science University
Collaborators: National Center of Neuromodulation for Rehabilitation, Collins Medical Trust, National Institutes of Health (NIH), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Department of Health and Human Services, National Institute of Neurological Disorders and Stroke (NINDS), National Center for Advancing Translational Sciences (NCATS)
Conditions
(from sponsor)		 Palsy Supranuclear, Supranuclear Palsy, Progressive
Related terms Supranuclear Palsy, Progressive
Enrollment 30 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov