Clinical Trial

Proton Versus Photon Therapy in Anal Squamous Cell Carcinoma

Study acronym: SWANCA
Recruiting
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Record status
This record was last updated April 3, 2025 (before its estimated April 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
Dosimetric studies suggest that radiotherapy with protons has a potential to reduce side effects compared to treatment with photons for patients with anal carcinoma (AC). There are so far no studies comparing these treatment techniques in a randomised setting. The aim of this study is to compare side effects following photon therapy versus proton therapy within the framework of a randomised controlled trial.
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2020-07-03; most recent amendment 2025-03-28.
Status change: Not Yet Recruiting → Recruiting 2021-04-08
Trial Details
NCT Number NCT04462042
Lead Sponsor Umeå University
Collaborators: Region Västerbotten, Uppsala County Council, Sweden
Conditions Anal Cancer Squamous Cell
Enrollment 100 participants
Start Date 2021-04-07
Primary Completion 2026-04-01 (estimated)
Study Completion 2031-03-28 (estimated)
Updated on ClinicalTrials.gov 2025-04-03