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This record was last updated April 13, 2025 (before its estimated September 30, 2026 completion). Its status may not reflect the trial's current state.
Record History
NotablePrimary and study completion dates: Sep 30, 2024 to Sep 30, 2026v12
NotableTrial status: Not Yet Recruiting to RecruitingPrimary and study completion dates: Sep 2024 to Sep 30, 2024 · Start date changed from estimate of Sep 1, 2023 to Sep 20, 2023 · Site details revisedv11Show 3 more changesShow less
Primary and study completion dates: Sep 2024 to Sep 30, 2024
Start date changed from estimate of Sep 1, 2023 to Sep 20, 2023
Site details revised
NotableStart date: Jun 1, 2023 to Sep 1, 2023Primary completion date: Jun 2024 to Sep 2024 · Completion date: Jul 2024 to Sep 2024v10Show 2 more changesShow less
Primary completion date: Jun 2024 to Sep 2024
Completion date: Jul 2024 to Sep 2024
NotableStart date: Jan 1, 2023 to Jun 1, 2023Primary completion date: Dec 2023 to Jun 2024 · Completion date: Jan 2024 to Jul 2024v9Show 2 more changesShow less
Primary completion date: Dec 2023 to Jun 2024
Completion date: Jan 2024 to Jul 2024
NotableStart date: Aug 1, 2022 to Jan 1, 2023v8
Show 6 earlier versionsHide 6 earlier versions
NotablePrimary completion date: Dec 2022 to Dec 2023Start date: Dec 1, 2021 to Aug 1, 2022 · Trial status: Recruiting to Not Yet Recruiting · Completion date: Jan 2023 to Jan 2024 · 1 morev7Show 4 more changesShow less
Start date: Dec 1, 2021 to Aug 1, 2022
Trial status: Recruiting to Not Yet Recruiting
Completion date: Jan 2023 to Jan 2024
Site details revised
NotableTrial status: Not Yet Recruiting to RecruitingStudy sites: 0 to 1 · Start date changed from estimate of Dec 2021 to Dec 1, 2021v6Show 2 more changesShow less
Study sites: 0 to 1
Start date changed from estimate of Dec 2021 to Dec 1, 2021
NotableStart date: Jun 2021 to Dec 2021v5
NotablePrimary completion date: Jun 4, 2022 to Dec 2022Start date: Dec 2020 to Jun 2021 · Completion date: Jul 1, 2022 to Jan 2023v4Show 2 more changesShow less
Start date: Dec 2020 to Jun 2021
Completion date: Jul 1, 2022 to Jan 2023
NotableStart date: Jul 1, 2020 to Dec 2020v3
NotableStart date: Jun 1, 2020 to Jul 1, 2020v2
MinorStudy First Submitted
Stopped: an ongoing trial was terminated, suspended or withdrawn.
Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Sciatic nerve block at the popliteal fossa is indicated for foot or ankle surgery, and the introduction of ultrasound guidance (USG) has improved the ease and accuracy of the performance of this block. Recent studies proved that subparaneural injection is associated with faster block onset, higher block success rate, and prolonged block duration suggesting subparaneural compartment of the sciatic nerve is a desirable site for local anaesthetic injection. Data from an ongoing trial in the investigator's institution comparing the block dynamics of subparaneural injection of 30ml 0.5% levobupivacaine (Chirocaine) above and below the bifurcation of the sciatic nerve at popliteal fossa has also shown that the time to 'readiness for surgery' was faster when the injection was performed below the bifurcation of the sciatic nerve. Lidocaine (Xylocaine) has a better pharmacokinetic and pharmacodynamics profile than levobupivacaine and is also widely used as local anaesthetic agent in clinical practice. Since there is no data comparing the block dynamics of lidocaine and levobupivacaine, this study aims to study and compare the block dynamics of lidocaine and levobupivacaine when given as a subparaneural injection below the bifurcation of the sciatic nerve at the popliteal fossa. In this study, the investigator hypothesizes that the use of lidocaine as the sole agent for this block will fasten the time to 'readiness for surgery' as compared to levobupivacaine when given as a subparaneural injection below the bifurcation of the sciatic nerve at the popliteal fossa.