Clinical Trial

Optimization of NIBS for Treatment of Addiction

Recruiting
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Summary
The purpose of this study is to assess the effects of transcranial Direct Current Stimulation (tDCS) applied in conjunction with Transcranial Ultrasound (TUS) for the treatment of addiction in opiate use disorder with chronic pain. The investigators hypothesize that there will be a decrease in drug use and improved psychosocial assessments with active stimulation, when compared to sham stimulation.
Protocol Amendment History 8 amendments
This ClinicalTrials.gov record has been amended 8 times since 2020-05-06; most recent amendment 2026-03-03.
Trial Details
NCT Number NCT04379115
Lead Sponsor Case Western Reserve University
Collaborators: Highland Instruments, Inc.
Conditions Opioid-use Disorder, Chronic Pain
Enrollment 126 participants
Start Date 2021-04-04
Primary Completion 2027-10-31 (estimated)
Study Completion 2027-10-31 (estimated)
Updated on ClinicalTrials.gov 2026-03-04