Individualized Assessment and Treatment for TMD

Temporomandibular/orofacial pain disorders (TMD) are a group of painful conditions with multiple determinants.This proposal has two main goals: 1) to test a highly individualized, adaptive treatment for TMD that has potential to be more effective than other psychosocial treatments; and 2) to discover the mechanisms by which psychosocial treatments work in chronic pain. TMD patients (N=160) will be randomized to receive standard care (STD) + an individualized assessment and treatment program (IATP) or to standard care + conventional cognitive-behavioral treatment (STD+CBT). It is expected that the STD+IATP treatment will yield lower pain, depression and interference scores over time than STD+CBT, and that changes in coping ability will mediate the treatment effects on outcomes.

NCT Number	NCT04376333
Lead Sponsor	UConn Health Collaborators: National Institute of Dental and Craniofacial Research (NIDCR)
Conditions	Temporomandibular Joint Disorders, Orofacial Pain
Enrollment	160 participants
Start Date	2021-02-03
Primary Completion	2027-03-31 (estimated)
Study Completion	2027-06-30 (estimated)
Updated on ClinicalTrials.gov	2026-07-22