Clinical Trial

Radiation Therapy Alone Versus Radiation Therapy Plus Radiofrequency Ablation (RFA)/Vertebral Augmentation

Active, Not Recruiting
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Record status
This record was last updated February 4, 2025 (before its estimated October 2025 completion). Its status may not reflect the trial's current state.
Summary
The spread of cancer to the spine is referred to as spine metastasis. Spine metastases are a common complication of cancer and are frequently associated with significant back pain. This study is being done to help improve treatment for back pain caused by spinal metastases by comparing the effectiveness of two standard treatments. These two treatments include radiation therapy (RT) alone versus radiation therapy combined with radiofrequency ablation, with or without vertebral augmentation (PVA/RFA). In addition to RT or RT with PVA/RFA, will be continued with current pain medications.
Protocol Amendment History 10 amendments
This ClinicalTrials.gov record has been amended 10 times since 2020-05-01; most recent amendment 2025-02-03.
Status change: Recruiting → Active, Not Recruiting 2025-02-03
Status change: Not Yet Recruiting → Recruiting 2020-09-18
Trial Details
NCT Number NCT04375891
Lead Sponsor Baptist Health South Florida
Collaborators: Medtronic
Conditions Oncology, Spine Metastases
Enrollment 63 participants
Start Date 2020-05-22
Primary Completion 2025-10 (estimated)
Study Completion 2027-07 (estimated)
Updated on ClinicalTrials.gov 2025-02-04