Clinical Trial

A Natural History Study to TRACK Brain and Spinal Cord Changes in Individuals with Friedreich Ataxia (TRACK-FA)

Study acronym: (TRACK-FA)
Active, Not Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated November 27, 2024 (before its estimated October 2025 completion). Its status may not reflect the trial's current state.
Summary
This is a natural history study prospectively investigating neuroimaging markers of disease progression in children and adults with Friedreich ataxia (FA). There will be three assessment periods (baseline, 12 and 24 months). The study will include approximately 200 individuals with FA and 100 matched controls recruited across the six international academic sites. Other assessments will include secondary clinical and cognitive markers, as well as exploratory blood markers.
Protocol Amendment History 12 amendments
This ClinicalTrials.gov record has been amended 12 times since 2020-04-14; most recent amendment 2024-11-25.
Status change: Recruiting → Active, Not Recruiting 2024-01-04
Status change: Not Yet Recruiting → Recruiting 2021-03-19
Trial Details
NCT Number NCT04349514
Lead Sponsor Monash University
Collaborators: University of Minnesota, RWTH Aachen University, University of Campinas, Brazil, Children's Hospital of Philadelphia, University of Florida, Friedreich's Ataxia Research Alliance, McGill University
Conditions Friedreich Ataxia
Enrollment 300 participants
Start Date 2021-02-10
Primary Completion 2025-10 (estimated)
Study Completion 2025-10 (estimated)
Updated on ClinicalTrials.gov 2024-11-27