Clinical Trial

Prospective Multicenter Randomized Comparative Study of the Treatment of de Novo Stenosis in Chron's Disease.

Study acronym: ENDOCIR
Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated August 19, 2025 (before its estimated April 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
Stenosis is one of the most frequent complications in patients with Crohn's disease (CD), causing greater morbidity and increasing the probability of repeated surgery and short bowel syndrome (1-3). Endoscopic balloon dilation (EBD) is clearly the treatment of choice for short stenoses located at the anastomosis of previous surgeries (4-6). However, there is no scientific evidence for determining the most appropriate treatment for de novo stenosis less than 10 cm in length (surgical versus endoscopic treatment), both in terms of efficacy and complications. Neither has it been established which of these two approaches has a greater impact on the quality of life of patients and on costs.
Protocol Amendment History 8 amendments
This ClinicalTrials.gov record has been amended 8 times since 2020-03-30; most recent amendment 2025-08-18.
Status change: Not Yet Recruiting → Recruiting 2023-02-23
Trial Details
NCT Number NCT04330846
Lead Sponsor Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa
Conditions Crohn Disease
Enrollment 40 participants
Start Date 2022-11-29
Primary Completion 2026-04-01 (estimated)
Study Completion 2027-04-01 (estimated)
Updated on ClinicalTrials.gov 2025-08-19