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The Beneficial Effects of Naps on Motor Learning

StatusRecruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 3 years 7 months later across 2 updates Aug 1, 2026 → Mar 30, 2030
See other at-risk trials from National Institute of Neurological Disorders and Stroke (NINDS)

Record History

The 50 most recent of 343 record versions are accounted for below. See every version on ClinicalTrials.gov ↗

  1. Primary and study completion pushed from Aug 1, 2027 to Mar 30, 2030 Eligibility criteria expanded, about 21 words Show 1 more changeShow less
    • Eligibility criteria expanded, about 21 words
  2. Primary and study completion pushed from Aug 1, 2026 to Aug 1, 2027v342
  3. 3 versions Re-verified since Jun 16, 2026, no change to tracked fieldsv339-v341
  4. Primary and study completion dates: Aug 1, 2025 to Aug 1, 2026v338
  5. Re-verified, no change to tracked fieldsv337
Show 43 earlier versionsHide 43 earlier versions
  1. Enrollment target: 174 to 199v336
  2. 8 versions Re-verified since Sep 6, 2024, no change to tracked fieldsv328-v335
  3. Eligibility criteria expanded, about 11 words Study description revisedv327 Show 1 more changeShow less
    • Study description revised

    See this version in full on ClinicalTrials.gov ↗

  4. 3 versions Re-verified since Apr 11, 2024, no change to tracked fieldsv324-v326
  5. Study description expanded, about 6 wordsv323 See this version in full on ClinicalTrials.gov ↗
  6. 6 versions Re-verified since Aug 7, 2023, no change to tracked fieldsv317-v322
  7. Study description shortened, about 62 wordsv316 See this version in full on ClinicalTrials.gov ↗
  8. Enrollment target: 138 to 174v315
  9. 3 versions Re-verified since Mar 18, 2023, no change to tracked fieldsv312-v314
  10. Interventions: MEG system (Device), MRI system (Device)v311
  11. Re-verified, no change to tracked fieldsv310
  12. Study Status, Study Descriptionv309
  13. Primary completion date: Mar 1, 2024 to Aug 1, 2025 Completion date: Dec 31, 2024 to Aug 1, 2025v308 Show 1 more changeShow less
    • Completion date: Dec 31, 2024 to Aug 1, 2025
  14. 14 versions Re-verified since Jun 13, 2022, no change to tracked fieldsv294-v307
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Background: Memory consolidation is the process by which memories become stable, long-term representations in the brain. Consolidation of a motor skill is dependent upon sleep. Some research shows that daytime naps improve people s motor performance and memory retention. Researchers want to find out how daytime naps may contribute to learning and support consolidation of motor skill memories. Objective: To learn the role of memory replay during wakeful rest and sleep (naps) in retaining a newly learned skill. Eligibility: English-speaking adults ages 18 and older with chronic stroke, or healthy, right-handed, English-speaking adults ages 18-35 and 50-80 Design: Participants will be screened with: * medical history * neurological history * medicine review * medical exam * neurological exam. Participants will have a magnetic resonance imaging (MRI) scan of the brain. For this, they will lie down in a scanner. The scanner makes loud noises, so they will wear earplugs. They will fill out an MRI screening form before each MRI. Participants will also have magnetoencephalography (MEG). MEG maps brain activity. It does this by recording the magnetic fields produced by naturally occurring electrical currents in the brain. For MEG, participants will lie down in the MEG room. Their eye movements may be recorded by a video camera. Participants will have behavior testing. They will practice typing random keys. Then they will repeatedly type a custom sequence that they see on a computer screen. Then they will take a 2-hour nap. Then they will type the same sequence again. Participants will have no more than 4 visits at the NIH over 3 months. Visits will last 2-4 hours each.
Trial Details
NCT Number NCT04312126
Lead Sponsor National Institute of Neurological Disorders and Stroke (NINDS)
Conditions Stroke
Enrollment 199 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov