Clinical Trial

Preeclampsia Postpartum Antihypertensive Treatment

Study acronym: P-PAT
Active, Not Recruiting Phase 3
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Summary
The goal of this study is to compare whether antihypertensive treatment in the postpartum period decreases postpartum hypertension and its associated maternal morbidity, including risk of readmission and healthcare utilization in comparison with no treatment. Women with preeclampsia diagnosed during the antepartum, intrapartum or postpartum period will be randomized to either initiate antihypertensive treatment or standard of care. We hypothesize that postpartum antihypertensive treatment of patients with preeclampsia will decrease risk of hospital readmission, healthcare utilization and the number of severe range blood pressures at postpartum follow-up visits.
Protocol Amendment History 8 amendments
This ClinicalTrials.gov record has been amended 8 times since 2020-03-04; most recent amendment 2026-07-16.
Status change: Recruiting → Active, Not Recruiting 2025-06-13
Status change: Not Yet Recruiting → Recruiting 2020-07-17
Trial Details
NCT Number NCT04298034
Lead Sponsor Medical College of Wisconsin
Conditions Preeclampsia, Hypertension in Pregnancy
Enrollment 300 participants
Start Date 2020-07-17
Primary Completion 2025-06-30 (estimated)
Study Completion 2026-09-30 (estimated)
Updated on ClinicalTrials.gov 2026-07-20