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Prospective Natural History Study of Retinitis Pigmentosa

Study acronym: PHENOROD2
StatusActive, Not Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated May 22, 2025 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.

Record History

See every version on ClinicalTrials.gov ↗

  1. Re-verified, no change to tracked fieldsv6
  2. Trial status: Recruiting to Active, Not Recruiting
    • Enrollment target: estimated 100 to confirmed 82
    • Site details revised at 2 of 2 sites
    v5
  3. Enrollment target: 80 to 100
    • Site details revised at 1 of 2 sites
    v4
  4. Primary and study completion dates: Oct 31, 2025 to Jun 30, 2026
    • Study sites: 1 to 2
    • Interventions: Mobility Test (Other), Ophthalmic examination (Other) to Mobility Test (Other), Ophthalmic examinations (Other)
    • Eligibility criteria expanded, about 6 words
    v3
  5. Primary completion date: Jun 1, 2021 to Oct 31, 2025
    • Study completion date: Oct 1, 2021 to Oct 31, 2025
    • Eligibility criteria expanded, about 46 words
    • Study description shortened, about 1 word
    v2
  6. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This is natural history study of rods and cones degenerations in patients with Retinitis Pigmentosa (RP) caused by pathogenic mutations in RHO, PDE6a or PDE6b gene mutations.
Trial Details
NCT Number NCT04285398
Lead Sponsor SparingVision
Conditions
(from sponsor)		 Retinitis Pigmentosa
Related terms Blindness, Cone-Rod Dystrophies, Eye Diseases, Retinal Diseases, Retinitis Pigmentosa, Vision Disorders
Enrollment 82 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov