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Evaluate the Safety, Immunologic, and Virologic Responses of Donor Derived (DD) HIV-Specific T-cells (HST) in HIV-infected Individuals Following Allogeneic Bone Marrow Transplantation (alloRESIST)

StatusActive, Not Recruiting
PhasePhase 1
Started2020-05-01
View on ClinicalTrials.gov ↗
This is a multi-site phase 1 study of the safety, immunologic and virologic responses of ex vivo expanded donor-derived (DD) HIV-1 multi-antigen specific T-cell (HST) with non-escaped epitope targeting (NEET) therapy as a therapeutic strategy in HIV-infected individuals following Allogeneic Bone Marrow Transplantation (alloBMT).

Amendment history 2 changes detected by DataLookout

2026-08-15
critical
Primary completion pushed: 2025-09 → 2026-11
2026-08-15
minor
Completion pushed: 2026-04 → 2026-12
Trial Details
NCT Number NCT04248192
Lead Sponsor Catherine Bollard
Conditions HIV-Infected Individuals
Enrollment 8 participants
Start Date 2020-05-01
Primary Completion 2026-11 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2026-08-14