Clinical Trial

Avr Thrombosis OutcoMe Study

Study acronym: ATOM
Recruiting
View on ClinicalTrials.gov →
Summary
This study aims to utilise novel biomarkers assessing thrombosis and thrombolysis (through a blood test), to identify patients undergoing either surgical aortic valve replacement (SAVR) or transcatheter aortic valve implantation (TAVI) who are at risk of thrombosis, and relate this to clinical thrombotic and thromboembolic adverse events and subclinical valve thrombosis, and identify the timeframe of greatest risk for valve thrombosis.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2020-01-16.
Status change: Not Yet Recruiting → Recruiting 2026-07-14
Trial Details
NCT Number NCT04234841
Lead Sponsor East and North Hertfordshire NHS Trust
Collaborators: Royal Brompton & Harefield NHS Foundation Trust
Conditions Aortic Stenosis
Enrollment 750 participants
Start Date 2020-02-01
Primary Completion 2028-01 (estimated)
Study Completion 2028-01 (estimated)
Updated on ClinicalTrials.gov 2026-07-15