A National Prospective Cohort of Patients With Idiopathic Nephrotic Syndrome Beginning in Childhood.

Pediatric idiopathic nephrotic syndrome (INS) is a rare disease for which the optimal therapeutic strategy has not yet been defined. A network of clinicians treating complicated forms of this disease (grouped within the Société de Néphrologie Pédiatrique, SNP) exists, but to date there is no prospective cohort following up these patients that would facilitate the development of cohort-nested trials. This absence of structured follow up makes it difficult to set up prospective studies. The main objective is to create a prospective cohort of pediatric INS patients to collect cases treated in SNP centers, to study their epidemiological characteristics, and to provide a basis for comparison for future cohort-nested trials.

NCT Number	NCT04207580
Lead Sponsor	University Hospital, Limoges
Conditions	Idiopathic Nephrotic Syndrome
Enrollment	1,180 participants
Start Date	2020-03-13
Primary Completion	2030-01 (estimated)
Study Completion	2048-01 (estimated)
Updated on ClinicalTrials.gov	2026-03-13