Prospective Evaluation of PRP and BMC Treatment to Accelerate Healing After ACL Reconstruction

This is a prospective, randomized, placebo-controlled trial to evaluate potential beneficial effects of leukocyte-poor platelet rich plasma and bone marrow concentrate on the healing and health of critical joint tissues in the knee following anterior cruciate ligament (ACL) reconstruction. Bone marrow contains stem cells which can change into cells of various different tissue types, while platelet rich plasma contains growth factors. This trial will compare the two procedures against placebo.

NCT Number	NCT04205656
Lead Sponsor	Steadman Philippon Research Institute Collaborators: United States Department of Defense, Office of Naval Research (ONR)
Conditions	Osteoarthritis, Knee
Enrollment	45 participants
Start Date	2020-01-02
Primary Completion	2024-07 (estimated)
Study Completion	2024-09 (estimated)
Updated on ClinicalTrials.gov	2024-07-16