Antibiotic Prophylaxis in Rhinoplasty

This study compares the efficacy of a single intra-operative (intravenous) dose of "cephalexin" (first generation cephalosporin) or "clindamycin" (lincosamides), alone versus both intra-operative (intravenous) dose of "cephalexin" (first generation cephalosporin) or "clindamycin" (lincosamides) and postoperative oral dose of "cephalexin" or "clindamycin" use in nasal surgery.

NCT Number	NCT04194216
Lead Sponsor	Stanford University Collaborators: Washington University School of Medicine, Vanderbilt University School of Medicine, University of Washington, Duke University, Harvard University, University of Kansas Medical Center, University of Cincinnati, Loma Linda University
Conditions	Nasal Obstruction, Nasal Surgical Procedures
Enrollment	864 participants
Start Date	2020-05-20
Primary Completion	2026-12-20 (estimated)
Study Completion	2027-04-20 (estimated)
Updated on ClinicalTrials.gov	2026-04-24