European Paediatric Non-Alcoholic Fatty Liver Disease Registry (EU-PNAFLD)

The EU-PNAFLD (The European Paediatric NALFD Registry) will be a network composed of European centres involved in the care of children with NAFLD, and will include Hepatologists, Endocrinologists, and Scientists, supported by relevant international specialists. This collaboration will build on existing infrastructure (local databases and bio-repositories) and will align with the adult European NAFLD Registry ("EPoS", Elucidating Pathways of Steatohepatitis study) to allow long-term follow-up supported by translational studies. Through an international, well-characterised large-scale cohort, we hope to: facilitate multi-centre clinical trials; extend our understanding of the key disease mechanisms of NAFLD; and establish the natural history of paediatric NAFLD.

NCT Number	NCT04190849
Lead Sponsor	Cambridge University Hospitals NHS Foundation Trust Collaborators: The European Association for the Study of the Liver, Children's Liver Disease Foundation
Conditions	Non-Alcoholic Fatty Liver Disease, Non-alcoholic Fatty Liver, Non-alcoholic Steatohepatitis
Enrollment	2,000 participants
Start Date	2017-11-14
Primary Completion	2047-11 (estimated)
Study Completion	2047-11 (estimated)
Updated on ClinicalTrials.gov	2022-03-04