Clinical Trial

The Youth Opioid Recovery Support (YORS) Intervention

Study acronym: YORS

Recruiting

Summary

Youth are disproportionately affected by the current opioid crisis with catastrophic consequences, and young adults with opioid use disorder (OUD) often struggle with adherence to relapse prevention medications. The Youth Opioid Recovery Support (YORS) model is a promising, innovative, wrap-around approach that addresses barriers to medication adherence and treatment engagement in an effort to improve public health outcomes in this vulnerable young adult population. This study seeks to refine the YORS intervention through stakeholder input and pilot iterative testing followed by an efficacy randomized controlled trial. This project will significantly contribute to our knowledge base of practical strategies to address the opioid crisis.

Protocol Amendment History 7 amendments

This ClinicalTrials.gov record has been amended 7 times since 2019-11-20; most recent amendment 2025-09-19.

Status change: Not Yet Recruiting → Recruiting 2020-05-12

Trial Details

NCT Number	NCT04173416
Lead Sponsor	Potomac Health Foundations Collaborators: National Institutes of Health (NIH), Friends Research Institute, Inc., National Center for Complementary and Integrative Health (NCCIH), National Institute on Drug Abuse (NIDA)
Conditions	Opioid-use Disorder, Medication Adherence
Enrollment	150 participants
Start Date	2020-02-17
Primary Completion	2026-08-31 (estimated)
Study Completion	2026-08-31 (estimated)
Updated on ClinicalTrials.gov	2025-09-24