Clinical Trial

Alpha-1 Blockade for Alcohol Use Disorder (AUD)

Study acronym: DOXY
Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
The goal of this research is to replicate findings previously conducted in a pilot trial and to understand, mechanistically, the role of stress in the development of AUD pharmacotherapies that target noradrenergic blockade.
Protocol Amendment History 12 amendments
This ClinicalTrials.gov record has been amended 12 times since 2019-10-21; most recent amendment 2026-03-18.
Status change: Not Yet Recruiting → Recruiting 2020-01-24
Trial Details
NCT Number NCT04135846
Lead Sponsor Brown University
Conditions Alcohol Use Disorder (AUD)
Enrollment 184 participants
Start Date 2019-12-19
Primary Completion 2026-08-31 (estimated)
Study Completion 2026-08-31 (estimated)
Updated on ClinicalTrials.gov 2026-03-20