Clinical Trial

Progressive Abduction Loading Therapy

Study acronym: PRALINE
Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
This study attempts to minimize the development of a common movement impairment following stroke known as "flexion synergy" that makes it extremely difficult to reach outward with the arm. Participants with acute/subacute stroke will receive one of two study interventions in addition to prescribed therapies in both inpatient rehabilitation and day-rehab. Participants will be followed for 1 year.
Protocol Amendment History 2 changes
notable Primary completion moved earlier: 2026-08-31 -> 2026-07-07 2026-08-11
minor Completion pushed: 2026-08-31 -> 2027-08-31 2026-08-11
Trial Details
NCT Number NCT04118998
Lead Sponsor Northwestern University
Collaborators: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Shirley Ryan AbilityLab, Marianjoy Rehabilitation Hospital & Clinics
Conditions Stroke, Acute
Enrollment 86 participants
Start Date 2021-08-27
Primary Completion 2026-07-07 (estimated)
Study Completion 2027-08-31 (estimated)
Updated on ClinicalTrials.gov 2026-08-10