Clinical Trial

Advancing Postmenopausal Preventive Therapy

Study acronym: APPT
Active, Not Recruiting Phase 2
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Summary
Advancing Postmenopausal Preventive Therapy (APPT) is a randomized, double-blinded, placebo-controlled trial designed to determine the effects of tissue selective estrogen complex (TSEC) therapy on the progression of subclinical atherosclerosis and cognitive decline in 360 healthy postmenopausal women.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2019-09-23; most recent amendment 2024-12-03.
Status change: Recruiting → Active, Not Recruiting 2024-12-03
Trial Details
NCT Number NCT04103476
Lead Sponsor University of Southern California
Collaborators: National Institute on Aging (NIA)
Conditions Atherosclerosis, Cognitive Decline
Enrollment 385 participants
Start Date 2021-04-13
Primary Completion 2026-10-31 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2024-12-05