Radial Vs. State-Of-The-Art Femoral Access for Bleeding and Access Site Complication Reduction in Cardiac Catheterization (REBIRTH)

This is a phase IV, prospective, open label, randomized-controlled study that will compare radial access with state-of-the-art femoral access in patients without ST-segment elevation acute myocardial infarction undergoing cardiac catheterization. Subjects will be randomized 1:1 into 2 treatment groups: radial access and state-of-the-art femoral access. Randomization will be performed in blocks of 50 per site. Similarly, a second sub-randomization will be performed in the femoral access group into use of 18 vs 21 gauge needles, also in a 1:1 fashion.

NCT Number	NCT04077762
Lead Sponsor	Minneapolis Heart Institute Foundation
Conditions	Patient Satisfaction, Vascular Access Complication
Enrollment	3,266 participants
Start Date	2019-11-15
Primary Completion	2027-08-19 (estimated)
Study Completion	2028-08-19 (estimated)
Updated on ClinicalTrials.gov	2025-01-24