Clinical Trial

Correlation of Radiological Lesions With Vestibular Function in Patients With Bilateral Vestibulopathy

Recruiting
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Summary
In 2014 radiologic lesions were detected at one or more semicircular canals using CT and MR imaging of temporal bone in subjects carrying the p.P51S mutation in COCH. These lesions are believed to present at more advanced stages of the hearing and vestibular deterioration. Since then, other authors have described similar lesions in advanced non-genetic hearing and vestibular impairment as well. The purpose of this study is therefore to assess the radiologic investigation using CT and MR imaging of temporal bone to all subjects presenting with bilateral vestibulopathy, using the Barany criteria, compared to the p.P51S population.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2019-08-26; most recent amendment 2021-08-24.
Status change: Not Yet Recruiting → Recruiting 2020-02-10
Trial Details
NCT Number NCT04070937
Lead Sponsor Jessa Hospital
Conditions Hearing Loss, Sensorineural, Bilateral Vestibular Deficiency, DFNA9, Radiology
Enrollment 40 participants
Start Date 2019-09-01
Primary Completion 2026-10-30 (estimated)
Study Completion 2026-10-30 (estimated)
Updated on ClinicalTrials.gov 2021-08-25