Clinical Trial

Short Post-surgical Antibiotic Therapy in Spine Infections - a Prospective, Randomized, Unblinded, Non-inferiority Trial

Recruiting
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Record status
This record was last updated February 21, 2025 (before its estimated February 28, 2025 completion). Its status may not reflect the trial's current state.
Summary
We implement a prospective, randomized, unblinded, non-inferiority trial regarding the duration of systemic, targeted antibiotic therapy after the first surgical debridement for spine infection; randomizing 1:1 between 1. Six and twelve weeks of antibiotic therapy if there is an implant left in place 2. Three and six weeks of antibiotic therapy if there is no implant left
Protocol Amendment History 6 amendments
This ClinicalTrials.gov record has been amended 6 times since 2019-08-05; most recent amendment 2025-02-20.
Status change: Not Yet Recruiting → Recruiting 2020-04-28
Trial Details
NCT Number NCT04048304
Lead Sponsor Balgrist University Hospital
Conditions Infection
Enrollment 236 participants
Start Date 2019-07-31
Primary Completion 2025-02-28 (estimated)
Study Completion 2025-12-31 (estimated)
Updated on ClinicalTrials.gov 2025-02-21