Clinical Trial

Behavioral and Neural Representations of Subjective Effort Cost

Recruiting
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Summary
The goal of this proposal is to understand the common and distinct behavioral and neural representations of subjective effort valuation, and how these representations are influenced by fatigue and changes in motivation. It is hypothesized that the brain will use overlapping and distinct neural circuits to represent cognitive and physical effort value, and that fatigue and enhanced motivation will influence the subjective value of effort.
Protocol Amendment History 6 amendments
This ClinicalTrials.gov record has been amended 6 times since 2019-07-30; most recent amendment 2026-01-23.
Trial Details
NCT Number NCT04041154
Lead Sponsor Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Collaborators: National Institute of Mental Health (NIMH)
Conditions Fatigue
Enrollment 185 participants
Start Date 2018-08-01
Primary Completion 2029-12-31 (estimated)
Study Completion 2029-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-01-26