Clinical Trial

Use of Antibiotic Irrigation to Decrease Wound Infections in Pediatric Perforated Appendicitis

Study acronym: PA protocol
Active, Not Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
The proposed study will investigate whether antibiotic irrigation using a gentamicin/clindamycin solution during laparoscopic appendectomy is superior in preventing postoperative wound infections and IAA in perforated appendicitis compared to suction without irrigation. This will be the first prospective study to compare these two options in pediatric PA.
Protocol Amendment History 8 amendments
This ClinicalTrials.gov record has been amended 8 times since 2019-07-29; most recent amendment 2026-01-26.
Status change: Recruiting → Active, Not Recruiting 2024-04-22
Trial Details
NCT Number NCT04039750
Lead Sponsor Prisma Health-Upstate
Conditions Perforated Appendicitis
Enrollment 200 participants
Start Date 2019-07-25
Primary Completion 2026-12 (estimated)
Study Completion 2026-12 (estimated)
Updated on ClinicalTrials.gov 2026-01-27