Clinical Trial

Evaluation of the Analgesia by Serratus Plane Block During Pleural Drainage in Intensive Care Unit.

Study acronym: SERRATUS
Recruiting Phase 3
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Summary
Pleural drainage under local anesthesia is a frequent practice in resuscitation, experienced as an unpleasant and painful event for patients. Pain management is an important issue for early rehabilitation, decrease hospitalisation's cost and shortening the length of stay in intensive care unit (ICU). A new type of locoregional anesthesia called Serratus plane block described by Blanco in 2013 showed a benefit in per and postoperative analgesia in thoracic surgery and carcinologic breast surgery, allowing a decrease in morphine use and an improvement of the patient's general satisfaction. Serratus plane block is a very effective technique in chest wall analgesia, easy and safe to perform, with few complications. No studies to date have evaluated this anesthetic practice in intensive care for pleural drainage. This technique could be used outside the operating room to improve the intensive care patients, who often have heavier pathologies and greater pain, such as patients with chest trauma or patients with cardiac or respiratory disease. The investigators would like to conduct a preliminary study of superiority in the CHU Amiens intensive care unit, to study the interest of the Serratus plane block in comparison with local anesthesia on the management of acute pain during pleural drainage.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2019-06-11; most recent amendment 2026-05-12.
Status change: Not Yet Recruiting → Recruiting 2021-07-15
Trial Details
NCT Number NCT03984656
Lead Sponsor Centre Hospitalier Universitaire, Amiens
Conditions Analgesia, Lidocaine, Intensive Care Unit
Enrollment 70 participants
Start Date 2019-06-04
Primary Completion 2026-09-06 (estimated)
Study Completion 2026-09-06 (estimated)
Updated on ClinicalTrials.gov 2026-05-13