Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT03893370 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.
MinorChangedRegistry marked status Unknown (sponsor has not verified the record since May 2024); last known: Active, Not Recruiting
NotablePrimary completion date: Apr 2024 to May 2025
Trial status: Recruiting to Active, Not Recruiting
Study sites: 30 to 27
v66
MinorRe-verified, no change to tracked fieldsv65
MinorPrimary completion date: Oct 2023 to Apr 2024
Study completion date: Sep 2024 to Sep 2026
Site details revised at 1 of 30 sites
v64
MinorSite details revised at 1 of 30 sitesv63
Show 45 earlier versionsHide 45 earlier versions
MinorSite details revised at 1 of 30 sitesv62
MinorStudy sites: 29 to 30v61
MinorSite contacts updated at 2 of 29 sitesv60
MinorStudy sites: 28 to 29v59
MinorSite details revised at 1 of 28 sitesv58
MinorSite details revised at 2 of 28 sitesv57
NotablePrimary completion date: Oct 2022 to Oct 2023
Study sites: 27 to 28
v56
MinorSite contacts updated at 5 of 27 sitesv55
MinorSite details revised at 1 of 27 sitesv54
MinorSite details revised at 1 of 27 sitesv53
MinorSite details revised at 1 of 27 sitesv52
MinorStudy sites revised (27)v51
MinorSite details revised at 1 of 27 sitesv50
MinorStudy sites: 26 to 27v49
MinorStudy sites: 25 to 26v48
MinorStudy sites: 24 to 25v47
MinorStudy sites: 23 to 24v46
MinorStudy sites: 22 to 23v45
MinorStudy sites: 21 to 22v44
MinorStudy sites: 22 to 21v43
MinorSite details revised at 1 of 22 sitesv42
MinorSite details revised at 2 of 22 sitesv41
MinorStudy sites: 21 to 22v40
MinorStudy sites: 20 to 21v39
MinorSite details revised at 2 of 20 sitesv38
MinorSite contacts updated at 1 of 20 sitesv37
NotableEnrollment target: 330 to 210v36Show 4 more changesShow less
Primary endpoints: 2 to 1
Study sites: 21 to 20
Eligibility criteria shortened, about 22 words
Secondary endpoints revised (5)
MinorStudy sites: 18 to 21v35
MinorSite details revised at 1 of 18 sitesv34
MinorSite details revised at 3 of 18 sitesv33
MinorSite details revised at 1 of 18 sitesv32
MinorStudy sites: 17 to 18v31
MinorSite details revised at 1 of 17 sitesv30
MinorSite contacts updated at 1 of 17 sitesv29
MinorSite contacts updated at 1 of 17 sitesv28
MinorStudy sites: 16 to 17v27
MinorSite contacts updated at 1 of 16 sitesv26
MinorSite details revised at 1 of 16 sitesv25
MinorSite details revised at 1 of 16 sitesv24
MinorSite details revised at 1 of 16 sitesv23
MinorStudy sites: 15 to 16v22
MinorStudy sites: 14 to 15v21
MinorSite details revised at 2 of 14 sitesv20
MinorSite details revised at 1 of 14 sitesv19
MinorSite contacts updated at 1 of 14 sitesv18
Stopped: an ongoing trial was terminated, suspended or withdrawn.
Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Chronic Obstructive Pulmonary Disease (COPD) is defined as an impaired ability to move air within the lungs and is a major public health problem that is projected to rank fifth worldwide in terms of disease burden and third in terms of mortality. Chronic bronchitis (CB) is a common clinical phenotype within the umbrella of a COPD diagnosis and is classically defined as chronic cough and sputum production for 3 months a year for 2 consecutive years2, but many studies have used different definitions to define it- chronic cough and sputum production for one year or cough and sputum production on most days of the week. CB is associated with multiple clinical consequences, including; the worsening of lung function decline, increasing risk of acute exacerbations of COPD, increased risk of developing pneumonia, reduced health related quality of life, and an increase in all-cause mortality.