Clinical Trial

Sex Differences in the Response to Abstinence From Alcohol.

Study acronym: SPAR
Recruiting Phase 1
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Summary
In laboratory animals, repeated cycles of abstinence from and return to alcohol drinking can lead to changes in alcohol intake. In a study of the effect of abstinence on drinking in humans, the investigators found evidence that abstinence affects drinking differently in women compared to men. In the present study, the investigators propose to study how men and women respond to abstinence, and whether this information can be used to improve intervention and prevention strategies.
Protocol Amendment History 12 amendments
This ClinicalTrials.gov record has been amended 12 times since 2019-01-30; most recent amendment 2026-05-12.
Status change: Not Yet Recruiting → Recruiting 2019-03-29
Trial Details
NCT Number NCT03827460
Lead Sponsor Indiana University
Collaborators: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Conditions Alcohol Use Disorder
Enrollment 160 participants
Start Date 2019-04-10
Primary Completion 2026-08-31 (estimated)
Study Completion 2028-08-31 (estimated)
Updated on ClinicalTrials.gov 2026-05-15