Clinical Trial

Post-Op Pain Control for Prophylactic Intramedullary Nailing.

Recruiting Phase 3
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Summary
Nationally, the opioid crisis has become a major epidemic with increasing mortality rates each year. Orthopedic surgeons routinely prescribe narcotics instead of NSAIDs for post-op pain control because of risk of delayed healing and nonunion due to NSAID use. Orthopedic oncology, however, has a unique subset of patients that undergo prophylactic placement of intramedullary femoral nails. Because no fracture is present, these patients do not rely on inflammatory healing factors, allowing for post-op NSAID use. This study sets out to determine the effect of post-op toradol use in addition to opioids compared to solely opioids in patients undergoing prophylactic nailing of the femur.
Protocol Amendment History 10 amendments
This ClinicalTrials.gov record has been amended 10 times since 2019-01-29; most recent amendment 2026-04-17.
Status change: Not Yet Recruiting → Recruiting 2019-02-20
Trial Details
NCT Number NCT03823534
Lead Sponsor St. Louis University
Conditions Bone Metastases, Lymphoma, Multiple Myeloma, Opioid Use, Pain
Enrollment 60 participants
Start Date 2019-02-20
Primary Completion 2026-12-31 (estimated)
Study Completion 2027-03-31 (estimated)
Updated on ClinicalTrials.gov 2026-04-22